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Product Name
:
DE-SPASM
Chemical Name
:
Mebeverine HCl
Therapeutic Category
:
Gastro-intestinal drugs
Pharmacologic Category
:
Antispasmodic
Pharmaceutical Form
:
Tablets
Composition
:
Mebeverine HCl 135mg
Lactation
Monitoring Parameters
Pharmacodynamics / Kinetics
Dosing
 
Dosing: Adult
One tablet ( 135 mg ) three times daily, 20 minutes before meals.
Use
 
DE-SPASM is used in the treatment of : - Irritable bowel syndrome. - Chronic irritable colon. - Spastic colitis.
DE-SPASM is used in the treatment of gastro-intestinal spasm secondary to organic lesions such as : gastric and duodenal ulcers, disease of the gall bladder and bile ducts.
Adverse Reactions
 
DE-SPASM may cause constipation.
Contraindications
 
Hypersensitivity to Mebeverine.
Warnings / Precautions Drug
 
DE-SPASM should be used with caution during pregnancy and lactation.
Pregnancy
 
C
Mechanism of Action
 
Mebeverine is an antisapasmodic with a direct action on the smooth muscle of the gastro-intestinal tract. Mebeverine stops the spasm and relieves the pain without affecting normal gut-motility. Mebeverine is rapidly and completely absorbed after oral administration and it is excreted into the urine.
 
   
 
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